The Curio Genomics story
We like hard problems.
Curio Genomics didn't start in genomics. The founders ran a software company building high-volume commerce systems for major retailers, and a friend, an ALS researcher, was drowning in NGS data: slow turnaround, tools only a specialist could operate. It looked like a big-data problem wearing a lab coat, so they took it on. For years CURIO was a nights-and-weekends project, thousands of hours of it, used by a small circle of academic researchers who kept asking for more.
Then in 2019, Arbor Biosciences arrived with a problem. They'd built an exome kit for the newly published wheat genome and couldn't validate it; the standard tools, all built for human data, choked on a genome five times that size and hexaploid besides. Six weeks later it was running in CURIO.
That settled it: agriculture was underserved in a way human genomics wasn't, and a platform that could handle wheat could handle anything. Curio Genomics spun out on its own in 2021 and built its early years on deep whole-genome research in grains: massive datasets, polyploid genomes, the work that was fun. Production turned out to have its own kind of hard. Sixty thousand cattle a year, breeding-season deadlines, where the platform doesn't get to have a bad week. Three years in, it hasn't. And, we're still having fun.